NOVEL RECURRENT CHROMOSOMAL ABERRATIONS DETECTED IN CLONAL PLASMA CELLS OF LIGHT CHAIN AMYLOIDOSIS PATIENTS SHOW POTENTIAL ADVERSE PROGNOSTIC EFFECT: FIRST RESULTS FROM A GENOME-WIDE COPY NUMBER ARRAY ANALYSIS

Novel recurrent chromosomal aberrations detected in clonal plasma cells of light chain amyloidosis patients show potential adverse prognostic effect: first results from a genome-wide copy number array analysis

Immunoglobulin light chain (AL) amyloidosis is a rare plasma cell dyscrasia characterized by the deposition of abnormal amyloid fibrils in multiple organs, thus impairing their function.In the largest cohort studied up to now of 118 CD138-purified plasma cell samples from previously untreated immunoglobulin light chain amyloidosis patients, we asse

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IMMUNOBIOLOGICAL CONTROL SYSTEM AND IMMUNOPATHOLOGICAL SYNDROMES

This publication is the first one in a series of brief Jodhpur Boots lectures dedicated to the characteristics of the immunobiological control system, aetiology and pathogenesis, which most frequently occur in the medical practices of the immunepathological syndromes: immunodeficiencies, allergic reactions, pathologic tolerance, graft-versus-host d

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